Ade, Cornell University!

Bad news, really bad news.

This morning I received a letter from Tri-institutional program in computational biology. They cannot offered me admission to their program. I was disappointed though I have prepared myself to face the worst result. I intend to study signal transduction network in The Tri-I program, but I am in fact not familiar with and intrigued in this field. My personal statement may seem not so persuasive.

I lost a good chance to enter an esteemed university, but also avoid entering an filed in which I show little passion. Keep confident. When we choose to open a door, we have to close another door. Hope is still there.

Ade, Cornell!

No News is Good News

NO NEWS IS GOOD NEWS

After last interview with Prof. Xiangzhong Zhou, I have been nervously wait for futther news, however, a whole week has passed, there still are not any news. I read the above sentence from a letter in BBS, no news is good news because they are still processing my application. Comfort me.

Enjoy your leisure time!

Jane Zhang will sing for World Peace One

I came to this news that Jane Zhang will sing for World Peace, a world peace organization. WP1 is recording a song Give Your Love in order to spread peace awareness and to raise fund for the organization.

Jane Zhang is the only Asian representative. If this is not enough to image what honor it means, here a list of singers who will also join (definitely a dream team )

U2, Madonna, Pink Floyd, Carlos Santana, Yes, Shakira, the Rolling Stones, Earth Wind & Fire, Paul McCartney, Elton John, Sting, David Bowie, Lionel Ritchie, the Goo Goo Dolls, Aerosmith, Bruce Springsteen, The Who, Led Zeppelin, Tina Turner, The Eagles, Pearl Jam, Moby, Alanis Morissette, Phil Collins, Eminem, Wyclef Jean, Will Smith, Usher, Mary J. Blige, JZ, Beyonce, Pink, Peter Gabriel, Eric Clapton, Alicia Keys, Lenny Kravitz, Janet Jackson, Baby Face, Greenday, Stevie Wonder, Chaka Khan, Patti Labelle, Aretha Franklin, Red Hot Chili Peppers, Justin Timberlake, Christina Aguilera, Celine Dion, Mariah Carey, Britney Spears, Bon Jovi, Outkast, Sarah McLachlan, Enya, Paul Simon, The Dixie Chicks, Willie Nelson, Brad Paisley, Garth Brooks, Rascal Flatts, Tricia Yearwood, Keith Urban, Shania Twain, Martina McBride, Faith Hill, Tim McGraw, Ricky Martin, Mark Antony, David Bisbal, Juanes, Luis Miguel, Olga Tanon, Alejandro Sanz, Gilberto Gil, Ivan Lins, Barbra Streisand, Bette Midler, Tony Bennett, Andrea Bocelli, Josh Groban, Autograph, Jane Zhang, David Lee, Prince Ali; and regional talent popular in many parts of the world.

I began to like Jane's personality (very cool) and voices when watching Super Girl 2005. Though my passion decrease later, I am still excited to hear this news. The world comes to appreciate Jane's talent. Jane, come on! your are the BEST!

Besides Jane's talent, the world's realization that one should not neglect the 13 billion Chinese people when thinking about world peace may also accelerate Jane's success. Anyway, congratulations to Jane.

The Dream of Red Chamber in wiki

I was really impressed by a piece of comment by Zhiyan Zhai when I was reading the Dream of Red Chamber. It says "I prey to God to create another Qin and another Zhi. It will be a great luck to the book and a great delight to us two"

能解者方有辛酸之泪，哭成此书。壬午除夕，书未成，芹为泪尽而逝。余尝哭芹，泪亦待尽。每意觅青埂峰再问石兄，余不遇獭头和尚何！怅怅！今而后惟愿造化主再出一芹一脂，是书何幸，余二人亦大快遂心于九泉矣。甲午八日泪笔。

I dreamed of being another Zhiyan Zhai expressing my ideas and feelings about this novel and sharing them with other alive. A wiki version of this book can record reversion history and provide collaboration between groups, and thus it will be good media to for people dreaming of being another Zhiyan Zhai like me. This media also involves now hot social network.

Fortunately, I came to know that Zoho release its wiki hosting service from TechCruch and I spent the whole night in tranferring a version of the Dream of Red Chamber to my wiki on Zoho. You can visit it at http://ryansonger.wiki.zoho.com/HomePage.html. It is still rather simple but I will add more materials in the future. And I welcome your comments and suggestions.

Avril Lavigne: Let Go

The quoted post was written in Sept 2006 when I first listened to Avril. Now during the long nervous and tedious time waiting for the application results, I began to listen to Avril again and naturally some new feelings. This post was originally published in WSH. I feel it better to move it to this blog, which is dedicated for entertainment.

This is the first time I listen to Avril Lavigne. Long before today I have noticed her beautiful name and grace posters. She rarely smiles. She impress you with a cool and pride attitude, something like a girl in one of Murakami Haruki's novel, Dance! Dance!Dance! this kind of girls have a talent to observe and control others. however, I didn't become a fan of Avril then because I have seen too many quick-coming-and -quick-going singers with a beautifle face but an ugly voice. I have a prejudice toward newly emerging actrees.

My idea changed when I come to losing grip, the first song of the album Complicated. Her style is a little like Sun Yanzi, relaxed and comfortable. I continued. the song complicated convert me to a funs of Avril. And then,Tomorrow. The voice souds so sweet that I feel my sweetheart whisp around my ears.

Recommendation & Review

• complicated free style, free attitude towards love
  
• skater boy leave social status and wealth aside, let us follow our heart and love each other. It is true we are nothing now but who knows what will we be like in the future.
  
• tomorrow sweet voice, soft style, however, the lyrics is too simple
• I'm with you I voe to take the girl's hand and take her to a happy place
• Mobile special and I cannot quite catch its idea
• Anything but ordinary A heart longing for freedom, crazy, brave love and fly
  

A good site to see lyrics. The layout is clean and comfortable with messy ads.
http://www.lyricsfreak.com/a/avril+lavigne/

Hurray! Interview Invitations from USC

After nearly a week's nervous waiting, I received my first interview invitation from USC yesterday. Prof. Xianghong Zhou wrote me the email, and it is possibly she will interview me. I visited her lab's website when I chose schools. She is a Chinese, assistant professor, with a sweet smile. Hopefully she will not be too strict with me in interview.

Well, know yourself and know your enemy, you will never be beaten even in a hundred of battles. I plan to read her papers in the next two days. Her research is centered around methodological study of integrating cross-platform microarray datasets. I have just read her paper of Gene Aging Nexus. She may has a rigorous requirement of statistics. (My disadvantage is my rather limited mathematical vocabulary!) I feel confident in my computer knowledge and programming ability.

Go on! Fighting!

Comments on Zhou's papers:
1. Gene Aging Nexus: A Web Database and Data Mining Platform for Microarray Data on Aging
keywords:
meta-analysis: by first extracting expression patterns form individual microarray datasets and then identifying recurrent signals, these approaches may enhance signal-noise separation.
differential expression analysis:
co-expression analysis: Zhou proposed a new method to mine regulatory modules in previous papers Mining dense subgraphs across massive biological networks for functional discovery.
no major biological breakthrough.

2. Integrative missing value estimation for microarray data
Question Answered:
Due to the inherent noise and the limitation of experimental systems, a microarray dataset on average has more than 5% missing values, affecting more than 60% of the genes. Such missing values made some subsequent analysis methods inapplicable or greatly decrease their performance. Thus the question of missing value estimation.

Basic Idea:
How to choose neighboring genes when not enough information is available in internal microarray dataset. Intuitively, if a set of genes frequently show expression similarity to the target gene over multiple data sets, they constitute a robust neighborhood which tend to show expression co-variations with the target gene.

other concepts:
LLS Local Least Square
Bayesian principle component analysis
singular value decomposition
support vector machines

Because everything is uncertain and that's why you should tell her

you should say it because everything is uncertain and that's why you should tell her~~

Yesterday I had a long msn talk with Paige. When she asked suddenly about my "girlfriend", I kept silent for a long time, and then replied, "I feel I like her but didn't expressed it. I don't know whether I should tell her since we are going to graduate and everything is uncertain." Maybe she is more intelligent than me.

Merry Christmas to all.

These days, I have been listening to six songs again and again.
MAGIC BOULEVARD by FRANCOIS FELDMAN
Down By The Sally Garden by Emi Fujita
Pour que tu m'aimes encore by Céline Dion
The Power Of The Dream by Celine Dion
Un garcon pas comme les autres by Céline Dion
Wa Su Re Na Gu Sa by Keiko Utoku